Mayo Clinic Proceedings study finds Cadence’s Remote Patient Care program reduces Medicare costs and patient hospitalizations
Peer-reviewed analysis of 5,872 Cadence patients across 15 U.S. states versus a matched control group (n=11,449) shows $1,302 decrease in total cost of care, 27% reduction in hospital admissions
November 28, 2025 – A multi-site, peer-reviewed study published in Mayo Clinic Proceedings: Innovations, Quality & Outcomes demonstrates Cadence’s Remote Patient Care (RPC) program significantly reduces total cost of care and hospitalizations for Medicare patients with chronic disease.
In a retrospective difference-in-difference analysis of 5,872 patients enrolled in Cadence RPC versus 11,449 propensity-matched controls across 15 U.S. states and large, diverse health systems, the data show:
Significant cost reductions:
- $1,302 decrease in total cost of care per patient per year (P<.01), inclusive of the incremental costs of remote monitoring services
- $1,428 decrease in inpatient spend per patient per year (P<.01)
Meaningful reductions in inpatient costs and admissions across high-cost conditions:
- Heart failure: -$10 per patient per month (PPPM); 64% decrease in hospitalizations
- Sepsis/infection -$21 PPPM; 57% decrease in hospitalizations
- Cardiac arrhythmias: -$12 PPPM; 27% decrease in hospitalizations
- Stroke: -$16 PPPM; 71% decrease in hospitalizations
Fewer hospitalizations and shorter lengths of stay:
- 27% reduction in hospitalizations:
- Cadence patients saw a reduction of 64 admissions per 1,000 patients per year
- Shorter hospital stays when admissions occurred, including:
- Infection/sepsis: 3.6 day reduction in length of hospital stay
- Stroke and related complications: 8.7 day reduction in length of hospital stay
Comparable outcomes for rural communities: Savings were comparable for patients in rural and underserved communities, showing that RPC can reduce spending and improve outcomes even in traditionally under-resourced settings.
As Medicare faces rising rates of chronic disease, solutions that truly improve control disease control and curb costs must be implemented effectively. This study demonstrates that Remote Patient Care delivers measurable impact: fewer hospitalizations, shorter lengths of stay, and reductions in total cost of care across some of the most costly conditions affecting older adults.
“For all of us working to strengthen Medicare, the most important takeaway is simple: 24/7 tech-enabled care can deliver real savings at national scale,” said Chris Altchek, CEO & Founder of Cadence.
“What this study shows is that when you give clinicians consistent, high-quality data and the infrastructure to act on it, outcomes change,” said Dr. David Feldman, Interventional Cardiology Fellow at Massachusetts General Hospital, Cadence medical advisor, and the abstract’s first author. "We are seeing consistent, proactive care resulting in earlier interventions and fewer undesired clinical events, which in turn directly impacts the frequency patients get hospitalized and cost to the system. That rare and meaningful combination is now very possible in chronic disease management.”
The paper, “The Impact of a Remote Patient Care Program on Healthcare Costs and Utilization Among Medicare Patients with Chronic Disease,” was authored by David I. Feldman MD, MPH (Massachusetts General), Spencer Reynolds MBA (Cadence), Sarine Babikian PhD (Cadence), Brian D. Stein MD, MS (Rush University Medical Center), Jessica Schlicher MD, MBA (Providence), Eve Cunningham MD, MBA (Cadence), Theodore Feldman MD (Baptist Health), Randall Curnow MD, MBA (Cadence), Jing Zheng MS (Humbi AI), Puneet Budhiraja MS (Humbi AI), Marat Fudim MD, MHS (Duke University Medical Center)
